Joachim Grotzinger: search on Z-Library

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1

Extinction of Cloudina and Namacalathus at the Precambrian-Cambrian boundary in Oman

Amthor, Joachim E., Grotzinger, John P., Schröder, Stefan, Bowring, Samuel A., Ramezani, Jahandar, Martin, Mark W., Matter, Albert

Journal:

Year:

2003

Language:

english

File:

PDF, 1.17 MB

english, 2003

2

Backbone assignments and secondary structure of the Escherichia coli enzyme-II mannitol a domain determined by heteronuclear three-dimensional NMR spectroscopy

Gerard J. A. Kroon, Klaas Dijkstra, Ruud M. Scheek, George T. Robillard, Joachim Grötzinger

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 2.12 MB

english, 1993

3

Lipid-Specific Membrane Activity of Human β-Defensin-3 †

Böhling, Arne, Hagge, Sven O., Roes, Stefanie, Podschun, Rainer, Sahly, Hany, Harder, Jürgen, Schröder, Jens-Michael, Grötzinger, Joachim, Seydel, Ulrich, Gutsmann, Thomas

Journal:

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

4

Functional characterization of three CYP21A2 sequence variants (p.A265V, p.W302S, p.D322G) employing a yeast co-expression system

Caroline Bleicken, Lourdes Loidi, Vivek Dhir, Silvia Parajes, Celsa Quinteiro, Fernando Dominguez, Joachim Grötzinger, Wolfgang G. Sippell, Felix G. Riepe, Wiebke Arlt, Nils Krone

Journal:

Year:

2009

Language:

english

File:

PDF, 658 KB

english, 2009

5

Proteolytic Cleavage Governs Interleukin-11 Trans-signaling

Lokau, Juliane, Nitz, Rebecca, Agthe, Maria, Monhasery, Niloufar, Aparicio-Siegmund, Samadhi, Schumacher, Neele, Wolf, Janina, Möller-Hackbarth, Katja, Waetzig, Georg H., Grötzinger, Joachim, Müller-N

Journal:

Year:

2016

Language:

english

File:

PDF, 3.87 MB

english, 2016

6

ADAM10 sheddase activation is controlled by cell membrane asymmetry

Bleibaum, Florian, Sommer, Anselm, Veit, Martin, Rabe, Björn, Andrä, Jörg, Kunzelmann, Karl, Nehls, Christian, Correa, Wilmar, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit, Reiss, Karina

Journal:

Journal of Molecular Cell Biology

Year:

2019

Language:

english

File:

PDF, 1.99 MB

english, 2019

7

Carbonate deposition and hydrocarbon reservoir development at the Precambrian–Cambrian boundary: The Ara Group in South Oman

Stefan Schröder, John P. Grotzinger, Joachim E. Amthor, Albert Matter

Journal:

Sedimentary Geology

Year:

2005

Language:

english

File:

PDF, 1001 KB

english, 2005

8

The IL-6/sIL-6R complex as a novel target for therapeutic approaches

Rose-John, Stefan, Waetzig, Georg H, Scheller, Jürgen, Grötzinger, Joachim, Seegert, Dirk

Journal:

Expert Opinion on Therapeutic Targets

Year:

2007

Language:

english

File:

PDF, 377 KB

english, 2007

9

Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain

Inken Lorenzen, Ahmad Trad, Joachim Grötzinger

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 838 KB

english, 2011

10

Dynamics of the gp130 cytokine complex: A model for assembly on the cellular membrane

Andreas Schroers, Oliver Hecht, Karl-Josef Kallen, Michael Pachta, Stefan Rose-John, Joachim Grötzinger

Journal:

Protein Science

Year:

2005

Language:

english

File:

PDF, 169 KB

english, 2005

11

Differential aggregation properties of alpha-synuclein isoforms

Bungeroth, May, Appenzeller, Silke, Regulin, Annika, Völker, Wolfgang, Lorenzen, Inken, Grötzinger, Joachim, Pendziwiat, Manuela, Kuhlenbäumer, Gregor

Journal:

Neurobiology of Aging

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

12

The Novel Mutation p.Trp147Arg of the Steroidogenic Acute Regulatory Protein Causes Classic Lipoid Congenital Adrenal Hyperplasia with Adrenal Insufficiency and 46,XY Disorder of Sex Development

Yüksel, Bilgin, Kulle, Alexandra E., Gürbüz, Fatih, Welzel, Maik, Kotan, Damla, Mengen, Eda, Holterhus, Paul-Martin, Topaloglu, Ali Kemal, Grötzinger, Joachim, Riepe, Felix G.

Journal:

Hormone Research in Paediatrics

Year:

2013

Language:

english

File:

PDF, 293 KB

english, 2013

13

Molecular mechanisms of cytokine receptor activation

Joachim Grötzinger

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2002

Language:

english

File:

PDF, 383 KB

english, 2002

14

The Soluble Interleukin-6 Receptor

STEFAN ROSE-JOHN, MARC EHLERS, JOACHIM GRÖTZINGER, JÜRGEN MÜLLBERG

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.05 MB

english, 1995

15

Psoriasin has divergent effects on the innate immune responses of murine glial cells

Jansen, Sandra, Kress, Eugenia, Fragoulis, Athanassios, Wruck, Christoph J., Wolf, Ronald, Grötzinger, Joachim, Michalek, Matthias, Pufe, Thomas, Tauber, Simone C., Brandenburg, Lars-Ove

Journal:

Journal of Neurochemistry

Year:

2017

Language:

english

File:

PDF, 977 KB

english, 2017

16

Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells

Susanne H. Hoischen, Petra Vollmer, Pia März, Suat Özbek, Katharina S. Götze, Christian Peschel, Thomas Jostock, Till Geib, Jürgen Müllberg, Sabine Mechtersheimer, Martina Fischer, Joachim Grötzinger,

Journal:

Year:

2000

Language:

english

File:

PDF, 688 KB

english, 2000

17

Unusual function of the activation loop in the protein kinase DYRK1A

Stephan Wiechmann, Hanna Czajkowska, Katrin de Graaf, Joachim Grötzinger, Hans-Georg Joost, Walter Becker

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 247 KB

english, 2003

18

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6

Bobby, Romel, Robustelli, Paul, Kralicek, Andrew V., Mobli, Mehdi, King, Glenn F., Grötzinger, Joachim, Dingley, Andrew J.

Journal:

Year:

2014

Language:

english

File:

PDF, 6.26 MB

english, 2014

19

Solution structure and functional studies of the highly potent equine antimicrobial peptide DEFA1

Michalek, Matthias, Jung, Sascha, Shomali, Mohammad R., Cauchard, Severine, Sönnichsen, Frank D., Grötzinger, Joachim

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

20

Recombinant p35 from Bacteria Can Form Interleukin (IL-)12, but Not IL-35

Aparicio-Siegmund, Samadhi, Moll, Jens M., Lokau, Juliane, Grusdat, Melanie, Schröder, Jutta, Plöhn, Svenja, Rose-John, Stefan, Grötzinger, Joachim, Lang, Philipp A., Scheller, Jürgen, Garbers, Christ

Journal:

Year:

2014

Language:

english

File:

PDF, 2.34 MB

english, 2014

21

CD9 Controls Integrin α5β1-Mediated Cell Adhesion by Modulating Its Association With the Metalloproteinase ADAM17

Machado-Pineda, Yesenia, Cardeñes, Beatriz, Reyes, Raquel, López-Martín, Soraya, Toribio, Víctor, Sánchez-Organero, Paula, Suarez, Henar, Grötzinger, Joachim, Lorenzen, Inken, Yáñez-Mó, María, Cabañas

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 3.52 MB

english, 2018

22

New perspectives on the design of cytokines and growth factors

Karl-Josef Kallen, Joachim Grötzinger, Stefan Rose-John

Journal:

Trends in Biotechnology

Year:

2000

Language:

english

File:

PDF, 488 KB

english, 2000

23

Identification of residues in the putative 5th helical region of human interleukin-6, important for activation of the IL-6 signal transducer, gp130

Just P.J Brakenhoff, Hanny Klaasse Bos, Joachim Grötzinger, Stefan Rose-John, Lucien A Aarden

Journal:

Year:

1996

Language:

english

File:

PDF, 491 KB

english, 1996

24

Therapeutic targeting of interleukin-6 trans-signaling does not affect the outcome of experimental tuberculosis

Jan Sodenkamp, Georg H. Waetzig, Jürgen Scheller, Dirk Seegert, Joachim Grötzinger, Stefan Rose-John, Stefan Ehlers, Christoph Hölscher

Journal:

Year:

2012

Language:

english

File:

PDF, 2.80 MB

english, 2012

25

Four Novel Missense Mutations in the CYP21A2 Gene Detected in Russian Patients Suffering from the Classical Form of Congenital Adrenal Hyperplasia: Identification, Functional Characterization, and Structural Analysis

Grischuk, Yulia, Rubtsov, Petr, Riepe, Felix G., Grötzinger, Joachim, Beljelarskaia, Svetlana, Prassolov, Vladimir, Kalintchenko, Natalya, Semitcheva, Tatyana, Peterkova, Valentina, Tiulpakov, Anatoly

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2006

Language:

english

File:

PDF, 703 KB

english, 2006

26

Synthetic deletion of the Interleukin 23 receptor (IL-23R) stalk region led to autonomous IL-23R homodimerization and activation

Hummel, Thorben M., Ackfeld, Theresa, Schönberg, Marco, Ciupka, Gregor, Schulz, Falk, Oberdoerster, Anne, Grötzinger, Joachim, Scheller, Jürgen, Floss, Doreen M.

Journal:

Molecular and Cellular Biology

Year:

2017

Language:

english

File:

PDF, 6.17 MB

english, 2017

27

The signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology region

Thomas Kernebeck, Stefan Pflanz, Peter C. Heinrich, Axel Wollmer, Joachim Grötzinger, Gerhard Müller-Newen, Günther Kurapkat, Stephan Grzesiek, Ruud M. Scheek, Klaas Dijkstra

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 2.19 MB

english, 1999

28

The structure of the unliganded extracellular domain of the interleukin-6 signal transducer gp130 in solution

Inken Lorenzen, Weifeng Shang, Markus Perbandt, Maxim V. Petoukhov, Dmitri I. Svergun, Georg H. Waetzig, Stefan Rose-John, Rolf Hilgenfeld, Joachim Grötzinger

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

29

Analysis of the Mechanism of Action of Anti-human Interleukin-6 and Anti-human Interleukin-6 Receptor-neutralising Monoclonal Antibodies

Michael Kalai, Fèlix A. Montero-julian, Just P. J. Brakenhoff, Véronique Fontaine, Lucas De Wit, Axel Wollmer, Hervé Brailly, Jean Content, Joachim Grötzinger

Journal:

Year:

1997

Language:

english

File:

PDF, 1.23 MB

english, 1997

30

Inactive conformation of an insulin despite its wild-type sequence

Gunther Kurapkat, Elke De Wolf, Joachim Grotzinger, Axel Wollmer

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 5.29 MB

english, 1997

31

Signal transducer gp130: biochemical characterization of the three membrane-proximal extracellular domains and evaluation of their oligomerization potential

PFLANZ, Stefan, KERNEBECK, Thomas, GIESE, Bernd, HERRMANN, Andreas, PACHTA-NICK, Michael, STAHL, Jürgen, WOLLMER, Axel, HEINRICH, Peter C., MÜLLER-NEWEN, Gerhard, GRÖTZINGER, Joachim

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 225 KB

english, 2001

32

The residue E351 is essential for the activity of human 21-hydroxylase: evidence from a naturally occurring novel point mutation compared with artificial mutants generated by single amino acid substitutions

Nils Krone, Felix G. Riepe, Joachim Grötzinger, Carl-Joachim Partsch, Jürgen Brämswig, Wolfgang G. Sippell

Journal:

Journal of Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 267 KB

english, 2005

33

Site-Directed Mutagenesis of Conserved Charged Residues in the Helical Region of the Human C5a Receptor : Arg206 Determines High-Affinity Binding Sites of C5a Receptor

Ute Raffetseder, Detlef Röper, Laurence Mery, Claudia Gietz, Andreas Klos, Joachim Grötzinger, Axel Wollmer, François Boulay, Jörg Köhl, Wilfried Bautsch

Journal:

Year:

1996

Language:

english

File:

PDF, 1.36 MB

english, 1996

34

Congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency: functional consequences of four CYP11B1 mutations

Menabò, Soara, Polat, Seher, Baldazzi, Lilia, Kulle, Alexandra E, Holterhus, Paul-Martin, Grötzinger, Joachim, Fanelli, Flaminia, Balsamo, Antonio, Riepe, Felix G

Journal:

European Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

35

Determination of disulfide linkages in antimicrobial peptides of the macin family by combination of top-down and bottom-up proteomics

Hung, Chien-Wen, Jung, Sascha, Grötzinger, Joachim, Gelhaus, Christoph, Leippe, Matthias, Tholey, Andreas

Journal:

Journal of Proteomics

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

36

The SNP rs4252548 (R112H) which is associated with reduced human height compromises the stability of IL-11

Lokau, Juliane, Göttert, Sascha, Arnold, Philipp, Düsterhöft, Stefan, López, David Massa, Grötzinger, Joachim, Garbers, Christoph

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2017

Language:

english

File:

PDF, 1.46 MB

english, 2017

37

Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2-Hydroxy Ketones

Hans Iding, Thomas Dünnwald, Lasse Greiner, Andreas Liese, Michael Müller, Petra Siegert, Joachim Grötzinger, Ayhan S. Demir, Martina Pohl

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 276 KB

english, 2000

38

The Signal Transducer Gp130 — Bacterial Expression, Refolding and Properties of the Carboxy-Terminal Domain of the Cytokine-Binding Module

Gerhard Müller-Newen, Stefan Pflanz, Ulrich Hassiepen, Jürgen Stahl, Axel Wollmer, Peter C. Heinrich, Joachim Grötzinger

Journal:

Year:

1997

Language:

english

File:

PDF, 716 KB

english, 1997

39

Different epitopes are required for gp130 activation by interleukin-6, oncostatin M and leukemia inhibitory factor

Andreas Timmermann, Stefan Pflanz, Joachim Grötzinger, Andrea Küster, Ingo Kurth, Vincent Pitard, Peter C. Heinrich, Gerhard Müller-Newen

Journal:

Year:

2000

Language:

english

File:

PDF, 396 KB

english, 2000

40

A Novel Entity of Clinically Isolated Adrenal Insufficiency Caused by a Partially Inactivating Mutation of the Gene Encoding for P450 Side Chain Cleavage Enzyme (CYP11A1)

Parajes, Silvia, Kamrath, Clemens, Rose, Ian T., Taylor, Angela E., Mooij, Christiaan F., Dhir, Vivek, Grötzinger, Joachim, Arlt, Wiebke, Krone, Nils

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

41

gp130 activation is regulated by D2–D3 interdomain connectivity

Schütt, Antje, Zacharias, Martin, Schneider, Nico, Horn, Silke, Grötzinger, Joachim, Rose‑John, Stefan, Schmidt‑Arras, Dirk

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

42

RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity

Mittelberger, Florian, Meyer, Cindy, Waetzig, Georg H, Zacharias, Martin, Valentini, Erica, Svergun, Dmitri I, Berg, Katharina, Lorenzen, Inken, Grötzinger, Joachim, Rose-John, Stefan, Hahn, Ulrich

Journal:

Year:

2015

Language:

english

File:

PDF, 882 KB

english, 2015

43

Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis

Marques, André R. A., Di Spiezio, Alessandro, Thießen, Niklas, Schmidt, Lina, Grötzinger, Joachim, Lüllmann-Rauch, Renate, Damme, Markus, Storck, Steffen E., Pietrzik, Claus U., Fogh, Jens, Bär, Julia

Journal:

Year:

2019

Language:

english

File:

PDF, 3.04 MB

english, 2019

44

A bioinformatical approach suggests the function of the autoimmune hepatitis target antigen soluble liver antigen/liver pancreas

Thomas Kernebeck, Ansgar W. Lohse, Joachim Grötzinger

Journal:

Year:

2001

Language:

english

File:

PDF, 316 KB

english, 2001

45

The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II

Inken Lorenzen, Juliane Lokau, Stefan Düsterhöft, Ahmad Trad, Christoph Garbers, Jürgen Scheller, Stefan Rose-John, Joachim Grötzinger

Journal:

Year:

2012

Language:

english

File:

PDF, 943 KB

english, 2012

46

Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptor

Peter BUBECK, Joachim GRÖTZINGER, Monica WINKLER, Jörg KÖHL, Axel WOLLMER, Andreas KLOS, Wilfried BAUTSCH

Journal:

Year:

1994

Language:

english

File:

PDF, 1.29 MB

english, 1994

47

Hexamer, tetramer or both: The IL6-IL-6R-gp130 complex

Inken Lorenzen, Markus Perbandt, Georg Wätzig, Stefan Rose-John, Rolf Hilgenfeld, Joachim Grötzinger

Journal:

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

48

Two N-Linked Glycans Differentially Control Maturation, Trafficking and Proteolysis, but not Activity of the IL-11 Receptor

Agthe, Maria, Garbers, Yvonne, Grötzinger, Joachim, Garbers, Christoph

Journal:

Cellular Physiology and Biochemistry

Year:

2018

Language:

english

File:

PDF, 3.04 MB

english, 2018

49

Alteration of the Substrate Specificity of Benzoylformate Decarboxylase from Pseudomonas putida by Directed Evolution

Bettina Lingen, Doris Kolter-Jung, Pascal Dünkelmann, Ralf Feldmann, Joachim Grötzinger, Martina Pohl, Michael Müller

Journal:

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

50

Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis

Ingrid Tacken, Heike Dahmen, Olivier Boisteau, Stéphane Minvielle, Yannick Jacques, Joachim Grötzinger, Andrea Küster, Ursula Horsten, Chrystel Blanc, Felix A. Montero-Julian, Peter C. Heinrich, Gerha

Journal:

Year:

1999

Language:

english

File:

PDF, 856 KB

english, 1999

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